Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WWOX All Species: 2.73
Human Site: T396 Identified Species: 4.62
UniProt: Q9NZC7 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZC7 NP_057457.1 414 46677 T396 Q S E E T A R T L W A L S E R
Chimpanzee Pan troglodytes XP_001144696 363 41022 R346 T L L F T L A R P F T K S M V
Rhesus Macaque Macaca mulatta XP_001105944 398 45056 R381 L H L F T S C R H E F G L S N
Dog Lupus familis XP_852623 383 43043 R366 D G S G L D G R I L R P V K A
Cat Felis silvestris
Mouse Mus musculus Q91WL8 414 46494 A396 Q S E E T A R A L W E L S E R
Rat Rattus norvegicus NP_001099658 356 40173 K339 H R N S W V Y K L L F T L A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505354 146 16628 V128 F S G R V V I V T G A N S G I
Chicken Gallus gallus Q5F389 414 46711 A396 R N E L T A V A L W E L S E R
Frog Xenopus laevis NP_001088080 143 16305 V126 G C D L S G K V A I V T G A N
Zebra Danio Brachydanio rerio Q803A8 412 46303 S393 Q D P A A A L S L W E L S E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 Q391 K S A A L Q Q Q L W K L S E N
Honey Bee Apis mellifera XP_395282 414 46992 R389 L D S A L A T R L W S V S Q E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789399 410 45991 A392 Q N T E L A T A L W D H T D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 E384 F E N Q L S Q E A S D V E K A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.5 84.7 82.8 N.A. 93.7 81.1 N.A. 26 83 29.2 71.9 N.A. 48.3 51.2 N.A. 56.2
Protein Similarity: 100 86.2 88.4 87.4 N.A. 96.1 83.8 N.A. 29.4 93 33.3 84.3 N.A. 65.2 66.6 N.A. 73.4
P-Site Identity: 100 13.3 6.6 0 N.A. 86.6 13.3 N.A. 20 60 0 53.3 N.A. 40 26.6 N.A. 33.3
P-Site Similarity: 100 20 13.3 13.3 N.A. 86.6 13.3 N.A. 20 73.3 20 60 N.A. 53.3 46.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 28.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 22 8 43 8 22 15 0 15 0 0 15 15 % A
% Cys: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 15 8 0 0 8 0 0 0 0 15 0 0 8 0 % D
% Glu: 0 8 22 22 0 0 0 8 0 8 22 0 8 36 8 % E
% Phe: 15 0 0 15 0 0 0 0 0 8 15 0 0 0 0 % F
% Gly: 8 8 8 8 0 8 8 0 0 8 0 8 8 8 0 % G
% His: 8 8 0 0 0 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 8 % I
% Lys: 8 0 0 0 0 0 8 8 0 0 8 8 0 15 0 % K
% Leu: 15 8 15 15 36 8 8 0 58 15 0 36 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 15 15 0 0 0 0 0 0 0 0 8 0 0 29 % N
% Pro: 0 0 8 0 0 0 0 0 8 0 0 8 0 0 0 % P
% Gln: 29 0 0 8 0 8 15 8 0 0 0 0 0 8 0 % Q
% Arg: 8 8 0 8 0 0 15 29 0 0 8 0 0 0 36 % R
% Ser: 0 29 15 8 8 15 0 8 0 8 8 0 58 8 0 % S
% Thr: 8 0 8 0 36 0 15 8 8 0 8 15 8 0 0 % T
% Val: 0 0 0 0 8 15 8 15 0 0 8 15 8 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 50 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _